Lion’s Mane isn’t just another mushroom it’s one of the most studied natural neuro support ingredients available today.
But not all Lion’s Mane products deliver what the science does.
ManeBrain was developed to bridge that gap, combining all three of Lion’s Mane’s key extract fractions, each playing a vital role in supporting brain structure, nerve growth factor (NGF) pathways, and mental clarity.
Most products use only fruiting body. But the Erinacines, the most powerful compounds shown in studies to influence NGF levels are found exclusively in the mycelium and require ethanol-based extraction to unlock.
ManeBrain delivers:
x Liquid-Fermented Mycelium Extract (3% Erinacines) – The core nootropic fraction
x Ethanol-Extracted Fruiting Body – To provide Hericenones (not soluble in water)
x 30% Beta-Glucan Hot Water Extract – Supporting immune and polysaccharide synergy
x Phosphatidylserine (PS) – A naturally occurring phospholipid found in healthy brain membranes
Every batch is HPLC-verified for active markers – ensuring purity, consistency, and precision.
for Maximum Potency
Each capsule contains potent 30:1 and 10:1 extract yielding a full-spectrum profile from over 13,500mg of raw mushroom material:
Extract Ratio Dry Equivalent Active Compounds
Mycelium Extract 30:1 6000mg 200mg 3% Erinacines
Fruiting Body Extract 30:1 6000mg 200mg 0.3% Hericenones (ethanol)
Beta-Glucan Extract 10:1 1500mg 150mg 30% Beta-Glucans
What does 30:1 mean? It means 30 parts of mushroom were reduced to 1 part of highly concentrated extract – removing fibre, water, and starch, and leaving only the most beneficial active compounds. That’s over 13 grams of raw material per capsule’s equivalent.
Why ManeBrain Is Different
x 3% Erinacines from Mycelium – The key compound found in human clinical studies
x Ethanol + Hot Water Extraction – Unlocking hericenones and beta-glucans
x Triple-Standardized, Full-Spectrum – No part of the mushroom left behind
x 13,500mg Dry Equivalent per Capsule – Potency few can match
x No Grain Grown Biomass – Pure mycelium and fruiting body only
x HPLC Verified – For identity, purity, and active compound levels
x Synergized with Phosphatidylserine – To support brain membrane fluidity and signalling
x Used in Clinical Protocols – Trusted by health professionals nationwide
What Makes Erinacines So Special?
Erinacines are a class of diterpenoids found only in Lion’s Mane mycelium. They are not water-soluble and cannot be extracted by hot water alone. Properly extracted with ethanol and verified through HPLC testing, Erinacines are the main compounds linked to the stimulation of NGF (nerve growth factor) in clinical research.
Many brands skip this step, using only hot water fruiting body powders with some modest BUT limited cognitive value. ManeBrain doesn’t compromise. It delivers all three fractions of Lion’s Mane just as nature (and clinical research) intended.
Each Capsule Contains:
x Liquid-Fermented Lion’s Mane Mycelium Extract – 200mg (30:1, 4% Erinacines)
x Fruiting Body Extract – 200mg (30:1, ethanol-based)
x Beta-Glucan Extract – 150mg (10:1, 30%)
x Phosphatidylserine – 50mg
x Vegetable Capsule (HPMC)
Directions for use: 1 capsule 1-2x per day or as directed by your health practitioner.
What’s in the box
1x glass bottle with 60 capsules of Mane Brain (Lion’s Mane Mushroom extract)
Disclaimer
DISCLAIMER: This product may be a complementary medicine and/or not have been evaluated and verified by the South African Health Products Regulatory Authority for its quality, safety or intended use. Use of this product is therefore not intended to compensate for diagnosis, treatment, cure, or mitigation of medical conditions and must not substitute the obtaining of medical advice from a registered health professional for any health or health-related conditions.


























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